A degenerative brain disease that mostly affects older persons is Alzheimer’s disease. Hormonal changes, particularly those associated with menopause, may increase Alzheimer’s risk in women. Estrogen, which declines during menopause, has neuroprotective effects. Inflammation and changes in menopause, may increase Alzheimer’s risk in women. Estrogen, which declines during menopause, has neuroprotective effects. Inflammation and changes in
brain chemistry due to hormonal fluctuations might also play a role.
While the exact mechanisms are still being studied, several theories have been proposed in some review articles:
Neuroprotective Effects of Estrogen: Estrogen has been shown to have neuroprotective effects, helping to protect brain cells from damage.
Inflammation: Hormonal fluctuations can contribute to increased inflammation, which in turn can aggravate neuro degeneration.
Neuro transmitter: Changes in hormone levels can affect brain chemicals known as neuro transmitters, leading to behavioral issues.
Some lifestyle strategies for prevention
* Hormone Replacement Therapy (HRT): HRT can help alleviate menopausal symptoms and may offer some protection against Alzheimer’s. However, it’s important to consult doctor as its important to assess the neurological status and compare the benefits and risk involved in HRT.
* Healthy diet: A diet rich in fruits, vegetables, whole grains, and healthy fats can support brain health. Consider incorporating foods rich in antioxidants, omega-3 fatty acids.
* Regular exercise: Physical activity can improve cognitive function and reduce the risk of dementia in general. Most days of the week, try to get in at least 30 minutes of moderate-intensity activity, or 150 minutes’ total.
* Cognitive skills: Engage in mentally stimulating activities like puzzles, reading, and learning new skills or language to keep your brain aptive.
* Stress management: Prolonged stress can negatively impact brain health. To handle stress, engage in relaxation practices like yoga, meditation, or deep breathing.
* Social connection: Maintaining strong social connections can help protect cognitive function. Spend quality time with family and engage in social events.
* Adequate sleep: Prioritize quality sleep to allow your brain to rest and detox.
* Regular health check-ups: Schedule regular check-ups with your healthcare provider to monitor your overall health, control sugar, blood pressure, lipid levels and address any underlying conditions that may increase your risk of Alzheimer’s.
It’s crucial to consult with a healthcare provider to discuss the potential benefits and risks of HRT and neurologists in case of memory related issues, behavioral problems, difficulty in doing daily activities, navigational problems for detailed neurological assessment.
Dr. Amrut S D, Associate Consultant Neurology, Manipal Hospital, Goa
